Epidemiological Studies vs n=1: What’s Optimal For Dietary Cholesterol?

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Papers referenced in the video:

Dietary Intakes of Eggs and Cholesterol in Relation to All-Cause and Heart Disease Mortality: A Prospective Cohort Study https://pubmed.ncbi.nlm.nih.gov/32400247/

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality https://pubmed.ncbi.nlm.nih.gov/30874756/

5 thoughts on “Epidemiological Studies vs n=1: What’s Optimal For Dietary Cholesterol?”

  1. Ron Hughes

    New subscriber to your website and I really appreciate the value of the information you provide. (And more importantly the evidence and credible sources which support it’s veracity.)
    With regards to dietary cholesterol how do you prevent shortfalls of choline while maintaining low levels of cholesterol? In most instances it seems food sources high in choline come with cholesterol. I recognize there are plant sources but typically they would require massive consumption to reach RDA levels.

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      1. Ron

        Hi Michael, I meant that if I make efforts to decrease dietary cholesterol, which for me probably averages 250 mg per day, there is a corresponding decrease in choline. (Because choline is most abundant in the foods with high levels of cholesterol.) I was wondering how you make up for the shortage? (or maybe it’s not a concern). I have a polymorphism that may warrant a higher dietary choline requirement.

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      2. Michael Lustgarten Post author

        Ah, gotcha. I get significant amounts of choline from plants, too-for example, in today’s diet, ~150 mg from mushrooms and lettuce. But note that together I ate ~1200 g of that combined to get that much choline.

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      3. Ron Hughes

        Roger, I target 500 mg of choline/day and at 60 years old my body can’t digest just that many vegetables. Thanks, and just want to reiterate how much I enjoy your site!

        Sent from Yahoo Mail for iPhone

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