Metformin Impairs Exercise Training-Related Improvements In Older Adults

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Papers referenced in the video:

Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a https://pubmed.ncbi.nlm.nih.gov/34725961/

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double-blind, placebo-controlled, multicenter trial: The MASTERS trial https://pubmed.ncbi.nlm.nih.gov/31557380/

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults https://pubmed.ncbi.nlm.nih.gov/30548390/

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