9 thoughts on “Quantifying Biological Age: Blood Test #6 in 2021”

1. Ron Hughes December 21, 2021 at 9:23 pm

   Another very informative video. Had you tweaked your diet since the last blood test or was it static? I am correct that you have settled on a protein intake of approximately 1.4G/KG? (In an effort to balance muscle protein synthesis and longevity)

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2. Michael Lustgarten Post authorDecember 21, 2021 at 9:30 pm

   Thanks Ron, I always tweak the diet after I analyze the data for the subsequent blood test. I’ve made several changes already-some of that will be in my next YouTube video, others I’m documenting on Patreon.

   For now, the protein intake is 1.4g/kg. I’ve been higher (~2g/kg), and I’m not opposed to higher, if the overall biomarker correlations suggests that it’s net beneficial.

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3. Ron Hughes December 22, 2021 at 9:14 pm

   Okay, from your other videos I’m guessing BUN would be one of the primary indicators, along with perhaps blood glucose concentration? I have been trying to tweak for the sweet spot myself as I’m turning 60 and want to balance muscle maintenance/growth and longevity.

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4. Ron Hughes December 23, 2021 at 8:05 pm

   By the way, don’t get a blood draw too close to a vax booster. Effected several biomarkers including a tripling of CRP. Came back down after a month.

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5. Ron January 26, 2022 at 5:22 pm

   Hi Michael,
   I saw a recent video featuring Peter Attia. During which he said that the U-shaped curve for LDL cholesterol and all-cause mortality is inaccurate/misleading. He said when people with people with preexisting illnesses were excluded all-cause mortality was lowest for the lowest levels of LDL. (apparently a number of illnesses predispose individuals to lower than normal LDL levels)
   What are your thoughts on this?
   Thanks.

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   1. Michael Lustgarten Post authorJanuary 26, 2022 at 8:27 pm

      Hi Ron, see the data in this video:

      Low LDL was significantly associated with an increased all-cause mortality risk especially when accounting for reverse causation. That said, I have another method to potentially assess whether low LDL is ok or not for optimal health: biomarker vs biomarker correlations. If low LDL is bad at the n=1 level, we’d expect to see a pattern reflected in other biomarkers-for example, higher glucose and inflammation. Is that the case? I’ve started some of those analyses on my YT channel, and there’s more to come. If there’s a weakness in my data, it’s that LDL is consistently < 100, which isn't good based on the published studies.

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      1. Ron February 7, 2022 at 10:39 pm

         Hi Michael,
         Another very engrossing video.
         Can you say which brand/type of sardines you eat daily? I like to work them in as much as possible but understand where they are sourced from can be indicative of the level of POPs.
         Also, which wearable do you like best?
         Thanks

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      2. Michael Lustgarten Post authorFebruary 8, 2022 at 4:32 pm

         Thanks Ron. the sardines are Crown Prince Natural Skinless and Boneless Sardines in Pure Olive Oil, and I’m currently wearing WHOOP.

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6. Ron January 27, 2022 at 11:15 am

   Unequivocal. Thank you!

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