Spermidine Impacts Health and Longevity

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Papers referenced in the video:

Polyamine-rich food decreases age-associated pathology and mortality in aged mice https://pubmed.ncbi.nlm.nih.gov/19735716/

Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats https://pubmed.ncbi.nlm.nih.gov/32285289/

Cardioprotection and lifespan extension by the natural polyamine spermidine https://pubmed.ncbi.nlm.nih.gov/27841876/

Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy https://pubmed.ncbi.nlm.nih.gov/28386016/

Higher spermidine intake is linked to lower mortality: a prospective population-based study https://pubmed.ncbi.nlm.nih.gov/29955838/

Polyamines in aging and disease https://pubmed.ncbi.nlm.nih.gov/21869457/

Dietary spermidine improves cognitive function https://pubmed.ncbi.nlm.nih.gov/33852843/

The positive effect of spermidine in older adults suffering from dementia : First results of a 3-month trial https://pubmed.ncbi.nlm.nih.gov/33211152/

The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/30388439/

Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline https://pubmed.ncbi.nlm.nih.gov/29315079/

A review of dietary polyamines: Formation, implications forgrowth and health and occurrence in foods https://www.sciencedirect.com/science/article/abs/pii/S0308814604002961

In vitro digestion of spermidine and amino acids in fresh and processed Agaricus bisporus mushroom https://pubmed.ncbi.nlm.nih.gov/33233206/

Decrease in polyamines with aging and their ingestion from food and drink https://pubmed.ncbi.nlm.nih.gov/16428322/

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