Have a look at my latest book update, including ~50 references that link microbial burden with all of the Hallmarks of Aging! https://www.amazon.com/dp/B01G48A88A
My average biological age in 2019 is 12 years younger than my chronological age (46y) based on the Phenotypic Age calculator (https://michaellustgarten.com/2019/11/01/biological-age-31-3y-chronological-age-46y/), and 16y younger based on aging.ai (https://michaellustgarten.com/2019/11/04/years-of-biological-aging-in-the-past-4-years/). One factor that likely contributes to my relatively youthful biological age is my diet. Shown below is my average daily dietary […]
In an earlier post (https://michaellustgarten.com/2018/06/26/maximizing-health-and-lifespan-is-calorie-restriction-essential/), I documented my aging.ai biologic age for 13 blood test measurements from 2016 – 2019. If you missed that post, here are those data: Note that note my average biologic age has slowly increased from 2016 to 2019, from 28y in 2016 (2 measurements), to […]
On June 10, 2019 (for the first time) I measured all of the blood test variables that are included in the biologic age calculator, Phenotypic Age, and ended up with a biological age = 35.39y (https://michaellustgarten.com/2019/09/09/quantifying-biological-age/). While that value is 23% younger than my chronological age (46y), I knew that […]
Platelets are one of the 19 variables that are included in the biological age calculator, aging.ai. The reference range is 150-400 platelets per nanoliter (*10^9/L), but within that range, what’s optimal? In a study of 21,635 adults older than 35y (average age wasn’t reported), platelets between 230-270 were associated with […]
The coronary artery calcification (CAC) score is a measure of how much calcification is in the coronary arteries, and accordingly, is an in vivo measure of atherosclerosis. Why is the CAC score important? Besides its role in atherosclerosis, risk of death for all causes goes up at any age as the […]
High sensitivity C-Reactive Protein (CRP) is one of the 10 variables included in the biological age calculator, PhenoAge (https://michaellustgarten.com/2019/09/09/quantifying-biological-age/). The reference range for CRP is 0 – 3 mg/L, but within that range, what’s optimal? To answer that question, it’s important to know how CRP changes during aging, and what […]
Mean corpuscular volume (MCV) is one of the 10 variables included in the biological age calculator, PhenoAge (see https://michaellustgarten.com/2019/09/09/quantifying-biological-age/). It’s calculated by dividing the fraction of the blood that contains RBCs (hematocrit) by RBCs (MCV = hematocrit/RBC), thereby identifying the average volume contained within red blood cells. Although the MCV reference […]
Circulating levels of white blood cells (WBCs) are one of the 10 variables used to quantify biological age with PhenoAge (https://michaellustgarten.com/2019/09/09/quantifying-biological-age). The reference range for WBCs is 4.5 – 11 *10^9 cells/L, but within that range, what’s optimal? Several studies have reported that WBCs greater than 5 are associated with an […]
In an earlier post, based on data from the Baltimore Longitidunal Study on Aging (BLSA), I suggested that total white blood cell (WBCs) counts between 3500 to 6000 cells per microliter of blood may be optimal for reducing disease risk and for maximizing longevity (https://michaellustgarten.com/2015/08/13/blood-testing-whats-optimal-for-wbc-levels/). However, within WBCs, neutrophils increase, […]
A few months ago, I presented data that a resting heart rate (RHR) ~40 beats per min is associated with maximally reduced risk of death from all causes (https://michaellustgarten.com/2019/02/02/resting-heart-rate-whats-optimal/). I started tracking my RHR data in August 2018, and I now have more than a full year of data. RHR […]