The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes and/or microbial products. The bacterial metabolite, LPS, increases during aging, and it negatively impacts mitochondrial function, thereby demonstrating a role for microbial products on one of the Hallmarks of Aging, mitochondrial dysfunction.
Here’s a recent interview where we discussed my journey from an undergraduate student that was interested in aging to scientist!
LDL is arguably the most debated biomarker in terms of what’s optimal for health. In the video, I present data showing that 100 – 140, not 50 – 70 mg/dL may be optimal in terms of minimizing disease risk and maximizing longevity.
White blood cells (WBCs) comprise many different cell types, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
Neutrophils, lymphocytes, and monocytes account for ~99% of WBCs, and accordingly, in the video I propose optimal ranges for these cell types in terms of health and longevity.
Here’s an interview that I did with Richard at Modern Healthspan, one of the best interviewers in aging!
Part I: Monitoring Biomarkers to Reverse Aging:
Part II, Diet, CR & Fasting:
Part III: Exercise, Protein
Part IV: Optimize Nutrients Through Diet
Part V: Inhibit CD38 to Optimize NAD
Part VI: Microbiome Impact on Muscle Metabolism
Part VII: Preferred Diet & Habit for Longevity
Michael Lustgarten 