Monthly Archives: December 2020

Microbial Products Affect the Hallmarks Of Aging: 1) Mitochondrial Function

The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes and/or microbial products. The bacterial metabolite, LPS, increases during aging, and it negatively impacts mitochondrial function, thereby demonstrating a role for microbial products on one of the Hallmarks of Aging, mitochondrial dysfunction.

LDL Cholesterol: What’s Optimal For Health And Longevity?

LDL is arguably the most debated biomarker in terms of what’s optimal for health. In the video, I present data showing that 100 – 140, not 50 – 70 mg/dL may be optimal in terms of minimizing disease risk and maximizing longevity.

Neutrophils, Lymphocytes, Monocytes: What’s Optimal For Health And Longevity?

White blood cells (WBCs) comprise many different cell types, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils.

Neutrophils, lymphocytes, and monocytes account for ~99% of WBCs, and accordingly, in the video I propose optimal ranges for these cell types in terms of health and longevity.

My Road to Maximize Lifespan – Monitor Biomarkers To Reverse Aging | Dr. Michael Lustgarten | Parts I – VII

Here’s an interview that I did with Richard at Modern Healthspan, one of the best interviewers in aging!

Part I: Monitoring Biomarkers to Reverse Aging:

Part II, Diet, CR & Fasting:

Part III: Exercise, Protein

Part IV: Optimize Nutrients Through Diet

Part V: Inhibit CD38 to Optimize NAD

Part VI: Microbiome Impact on Muscle Metabolism

Part VII: Preferred Diet & Habit for Longevity