Category Archives: NAD

Kynurenine/Tryptophan Ratio: More Insight Into The De Novo NAD Synthesis Pathway

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At-Home Metabolomics: https://iollo.com?ref=michael-lustgarten

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten

Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv
Use Code: CONQUERAGING

At-Home Blood Testing: https://getquantify.io/mlustgarten

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Papers referenced in the video:
Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging
https://pubmed.ncbi.nlm.nih.gov/34117761/

Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality The Hordaland Health Study
https://pubmed.ncbi.nlm.nih.gov/26823439/

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Vitamin B6: Did It Increase NAD? (Test Results)

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Discount Links:
NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten

Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv
Use Code: CONQUERAGING

At-Home Blood Testing: https://getquantify.io/mlustgarten

Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

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NAD Test #3: Impact of 1000 mg NMN/d?

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Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten

Epigenetic Testing: https://bit.ly/3Rken0n
Use Code: CONQUERAGING!

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NAD Test #2: Impact of NMN?

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Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome: https://www.bristlehealth.com/?ref=michaellustgarten

Epigenetic Testing: https://bit.ly/3Rken0n
Use Code: CONQUERAGING!

At-Home Blood Testing: https://getquantify.io/mlustgarten

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Quantifying NAD: Test #1 in 2023

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Join us on Patreon!
https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
NAD+ Quantification
Use Code: ConquerAging At Checkout
https://www.jinfiniti.com/intracellular-nad-test/

Green Tea
https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome
Use Code: ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

Epigenetic Testing
CONQUERAGING!
https://bit.ly/3Rken0n

At-Home Blood Testing
https://getquantify.io/mlustgarten

Diet Tracking
https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

If you’d like to support the channel, you can do that with the website, Buy Me A Coffee:
https://www.buymeacoffee.com/mlhnrca

Conquer Aging Or Die Trying Merch!
https://my-store-d4e7df.creator-spring.com/

Papers referenced in the video:
NAD and the aging process: Role in life, death and everything in between
https://pubmed.ncbi.nlm.nih.gov/27825999/

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence
https://pubmed.ncbi.nlm.nih.gov/29514064/

Bacteria boost host NAD metabolism
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762504/

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome
https://pubmed.ncbi.nlm.nih.gov/23172919/

SIRT6 Positively Affects The Hallmarks Of Aging And Extends Lifespan

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Papers referenced in the video:

Sirtuins, Healthspan, and Longevity in Mammals https://www.sciencedirect.com/science…

Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH https://pubmed.ncbi.nlm.nih.gov/24011…

Resveratrol improves health and survival of mice on a high-calorie diet https://pubmed.ncbi.nlm.nih.gov/17086…

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice https://pubmed.ncbi.nlm.nih.gov/20974…

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer https://www.nature.com/articles/ncomm…

Restoration of energy homeostasis by SIRT6 extends healthy lifespan https://pubmed.ncbi.nlm.nih.gov/34050…

The sirtuin SIRT6 regulates lifespan in male mice https://pubmed.ncbi.nlm.nih.gov/22367…

SIRT6 in Senescence and Aging-Related Cardiovascular Diseases https://pubmed.ncbi.nlm.nih.gov/33855…

Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling https://pubmed.ncbi.nlm.nih.gov/26940…

Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6 https://pubmed.ncbi.nlm.nih.gov/27101…

A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer’s Disease, Aging, Cancer, Inflammation, and Diabetes https://pubmed.ncbi.nlm.nih.gov/33920…

Acute Exercise Leads to Regulation of Telomere Associated Genes and MicroR A Expression in Immune Cells https://pubmed.ncbi.nlm.nih.gov/24752…

The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men https://pubmed.ncbi.nlm.nih.gov/32919…

Are There Foods That Can Increase NAD? (Part II)

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Papers referenced in the video:

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence: https://pubmed.ncbi.nlm.nih.gov/29514…

NAD and the aging process: Role in life, death and everything in between: https://pubmed.ncbi.nlm.nih.gov/27825…

Flavonoids as inhibitors of human CD38: https://pubmed.ncbi.nlm.nih.gov/21641…

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome: https://pubmed.ncbi.nlm.nih.gov/23172…

Characterization of Anthocyanins and Proanthocyanidins in Some Cultivars of Ribes, Aronia, and Sambucus and Their Antioxidant Capacity: https://pubmed.ncbi.nlm.nih.gov/15612…

Flavonoid glycosides and antioxidant capacity of various blackberry, blueberry and red grape genotypes determined by high-performance liquid chromatography/mass spectrometry: https://onlinelibrary.wiley.com/doi/1…

USDA Database for the Flavonoid Content of Selected Foods: https://www.ars.usda.gov/arsuserfiles… Large changes in NAD levels associated with CD38 expression during HL-60 cell differentiation: https://pubmed.ncbi.nlm.nih.gov/24216…

Effect of genotype and environment on flavonoid concentration and profile of black sorghum grains (incorrectly indicated as Dykes et al. 2013): https://www.sciencedirect.com/science…

Luteolinidin Protects the Post-ischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H): https://jpet.aspetjournals.org/conten…SHOW LESS

Gut Bacteria Boost Host NAD Metabolism

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Papers referenced in the video:

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi.nlm.nih.gov/32130883/

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism: https://pubmed.ncbi.nlm.nih.gov/27304511/

Aerobic and resistance exercise training reverses age-dependent decline in NAD + salvage capacity in human skeletal muscle: https://pubmed.ncbi.nlm.nih.gov/31207144/