Bile Acids: The Next Frontier In Longevity?

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Papers referenced in the video:

Glycine supplementation extends lifespan of male and female mice

Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation

17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex

Metagenomic and metabolomic remodeling in nonagenarians and centenarians and its association with genetic and socioeconomic factors

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

Alterations in xenobiotic metabolism in the long-lived Little mice Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

Bile Acids: A Communication Channel in the Gut-Brain Axis


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