Maximal lifespan in calorie restricted (CR) mice can range from 45 – 55 months. In this video, I present data for 3 studies on rapamycin-can it beat CR for maximal lifespan?
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Fungi In The Blood, Fungi In The Brain: Rapamycin To The Rescue?
Thu Aug 27 , 2020
The incidence of fungi bloodstream infections increases during aging-is that a potential explanation for the presence of fungi in the brains of Alzheimer’s disease patients? Rapamycin is a known antifungal-is it effective against fungi that are found in the blood and brain?
Not aware that CR provides same benefits in monkeys if started from human age 3 equivalent, so a comparison against the adult onset mouse CR gains may be necessary. NIA J/A onset rhesus monkeys on CR M & F both lived shorter than control – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247583/