Ergothioneine: A ‘Longevity Vitamin’ With Potential Benefits For Age-Related Outcomes?

Papers referenced in the video:

Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity: https://www.ncbi.nlm.nih.gov/pmc/arti…

Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration? https://pubmed.ncbi.nlm.nih.gov/27444…

Is ergothioneine a ‘longevity vitamin’ limited in the American diet? https://www.ncbi.nlm.nih.gov/pmc/arti…

Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility: https://pubmed.ncbi.nlm.nih.gov/32295…

Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease: https://pubmed.ncbi.nlm.nih.gov/31672…

Ergothioneine – a diet‐derived antioxidant with therapeutic potential: https://febs.onlinelibrary.wiley.com/…

Ergothioneine, a metabolite of the gut bacterium Lactobacillus reuteri, protects against stress-induced sleep disturbances: https://www.nature.com/articles/s4139…

Michael Lustgarten

Ph.D, Physiology, University of Texas Health Science Center at San Antonio, 2009 B.S., Biochemistry, Queens College, 2003 B.A, English Textual Studies, 1994, Syracuse University

2 thoughts on “Ergothioneine: A ‘Longevity Vitamin’ With Potential Benefits For Age-Related Outcomes?

  1. Not sure where to post this question. Dr. L: I know you have studied frailty and muscle loss in older adults and I’m curious what you think about “power plate” technology described here. These machines are not inexpensive; I wonder if there are any control studies proving its effectiveness. Thanks. https://www.youtube.com/watch?v=IIl8hL06i-M&t=11s

    1. My preference is good-old-fashioned exercise, whether it’s via the power plate or anything else. The key is consistency, week-to-week, and beyond. There’s no magic pill for improved fitness.

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