Papers referenced in the video: Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity: https://www.ncbi.nlm.nih.gov/pmc/arti… Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration? https://pubmed.ncbi.nlm.nih.gov/27444… Is ergothioneine a ‘longevity vitamin’ limited […]
microbiome
Papers referenced in the video: Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi.nlm.nih.gov/32130883/ CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism: https://pubmed.ncbi.nlm.nih.gov/27304511/ Aerobic and resistance exercise training reverses age-dependent decline in NAD + salvage capacity in human skeletal muscle: https://pubmed.ncbi.nlm.nih.gov/31207144/
Here’s the first interview clip (of a series) with Modern Healthspan on YouTube where we discuss the role of the microbiome on health and longevity: Part II: Skin, Oral Microbiome & Immune System Part III: Optimal Health with Soluble Fiber Part IV – Microbial Burden & Hallmarks of Aging Part […]
In the video below, Steve Hill from Lifespan.io and I talk about findings from a recent paper (https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200306) that supports a role for the gut microbiome on Alxheimer’s disease. Check it out!
Germ-free mice (animals don’t have a microbiome) live longer than microbiome-containing mice, but it’s impractical for people to live in a bubble for their entire lifespan. As a more practical approach, which microbiome-derived factors impact lifespan, and can they be modified? Dietary supplementation with acarbose increases lifespan, and one reason […]
How does the gut microbiome and its metabolic products affect muscle mass, muscle composition, and physical function? In this presentation, I review the evidence, then I present recent data from our group.
Here’s a link to a recent interview, https://biohackstack.com/posts/michael-lustgarten/?fbclid=IwAR059Jf6eT4SyvsqTxHaSir2hQuXKjV5R6kLg-7Df1Kc4c7ZKM6Tw-0qRwY Including: How (and why) did you get involved in research in aging and the human microbiome? How did you get started in health optimization / quantified-self? What are your thoughts on biological age testing? Which tests (epigenetic, blood biomarkers, telomere, etc) and […]
Here’s my latest academic paper! mdpi.com/2072-6643/12/1/106
Have a listen, I was on Generation Bold Radio yesterday, 9.14.2019! https://www.generationboldradio.us/
Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults https://www.sciencedirect.com/science/article/pii/S0531556519304772
Microbiome Webinar featuring me, and Drs. Amy Proal and Cosmo Mielke! For more info, https://www.amazon.com/dp/B01G48A88A
Deep sleep, the stage of sleep also known as “slow wave sleep” declines during aging. Based on a meta-analysis of 65 studies representing 3,577 subjects (aged 5 years to 102 years; Ohayon et al. 2004), slow wave sleep, expressed as a percentage of total sleep time decreases during aging from 25% […]
Tufts Nutrition Magazine, 1/2019 Please have a look at my book, if you’re interested!
Paper #1: Here I propose that the poor muscle composition (muscle that has fat in it) found in older adults may be related to an increased systemic microbial burden: https://www.ncbi.nlm.nih.gov/pubmed/29030163 Paper #2: In this review, we discuss the emerging gut-muscle axis: https://www.ncbi.nlm.nih.gov/pubmed/29058056 If you’re interested, please have a […]
If you’re interested, please have a look at my book!
https://vimeo.com/174783072 If you’re interested, please have a look at my book! https://www.amazon.com/Microbial-Burden-Major-Age-Related-Disease-ebook/dp/B01G48A88A
