Tag Archives: NAD+

Are There Foods That Can Increase NAD? (Part II)

Papers referenced in the video:

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence: https://pubmed.ncbi.nlm.nih.gov/29514…

NAD and the aging process: Role in life, death and everything in between: https://pubmed.ncbi.nlm.nih.gov/27825…

Flavonoids as inhibitors of human CD38: https://pubmed.ncbi.nlm.nih.gov/21641…

Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome: https://pubmed.ncbi.nlm.nih.gov/23172…

Characterization of Anthocyanins and Proanthocyanidins in Some Cultivars of Ribes, Aronia, and Sambucus and Their Antioxidant Capacity: https://pubmed.ncbi.nlm.nih.gov/15612…

Flavonoid glycosides and antioxidant capacity of various blackberry, blueberry and red grape genotypes determined by high-performance liquid chromatography/mass spectrometry: https://onlinelibrary.wiley.com/doi/1…

USDA Database for the Flavonoid Content of Selected Foods: https://www.ars.usda.gov/arsuserfiles… Large changes in NAD levels associated with CD38 expression during HL-60 cell differentiation: https://pubmed.ncbi.nlm.nih.gov/24216…

Effect of genotype and environment on flavonoid concentration and profile of black sorghum grains (incorrectly indicated as Dykes et al. 2013): https://www.sciencedirect.com/science…

Luteolinidin Protects the Post-ischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H): https://jpet.aspetjournals.org/conten…SHOW LESS

Gut Bacteria Boost Host NAD Metabolism

Papers referenced in the video:

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi.nlm.nih.gov/32130883/

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism: https://pubmed.ncbi.nlm.nih.gov/27304511/

Aerobic and resistance exercise training reverses age-dependent decline in NAD + salvage capacity in human skeletal muscle: https://pubmed.ncbi.nlm.nih.gov/31207144/

Apigenin Increases Muscle Mass And Improves Muscle Function In Both Young And Old Mice

In an earlier video, I presented data for apigenin’s ability to increase levels of NAD+. In addition to apigenin’s impact on NAD+, apigenin supplementation increases muscle mass, strength, and treadmill running distance in both young and old mice.

Video link for NAD+ is increased in response to apigenin: https://youtu.be/5-2YoGctcCk?list=UUT…

Paper links:

Apigenin enhances skeletal muscle hypertrophy and myoblast differentiation by regulating Prmt7: https://pubmed.ncbi.nlm.nih.gov/29108…

Apigenin Ameliorates the Obesity‐Induced Skeletal Muscle Atrophy by Attenuating Mitochondrial Dysfunction in the Muscle of Obese Mice: https://onlinelibrary.wiley.com/doi/a…

Antioxidant Apigenin Relieves Age-Related Muscle Atrophy by Inhibiting Oxidative Stress and Hyperactive Mitophagy and Apoptosis in Skeletal Muscle of Mice: https://pubmed.ncbi.nlm.nih.gov/32857…