Tag Archives: lifespan

U-Shaped Association Between Duration Of Sports Activities And Mortality

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Paper referenced in the video: U-Shaped Association Between Duration of Sports Activities and Mortality: Copenhagen City Heart Study https://www.mayoclinicproceedings.org/article/S0025-6196(21)00475-4/fulltext

Ergothioneine Extends Lifespan (in flies)

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Papers referenced in the video:

Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation https://pubmed.ncbi.nlm.nih.gov/34877949/

Is ergothioneine a ‘longevity vitamin’ limited in the American diet? https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7681161/

Spermidine Impacts Health and Longevity

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Papers referenced in the video:

Polyamine-rich food decreases age-associated pathology and mortality in aged mice https://pubmed.ncbi.nlm.nih.gov/19735716/

Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats https://pubmed.ncbi.nlm.nih.gov/32285289/

Cardioprotection and lifespan extension by the natural polyamine spermidine https://pubmed.ncbi.nlm.nih.gov/27841876/

Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy https://pubmed.ncbi.nlm.nih.gov/28386016/

Higher spermidine intake is linked to lower mortality: a prospective population-based study https://pubmed.ncbi.nlm.nih.gov/29955838/

Polyamines in aging and disease https://pubmed.ncbi.nlm.nih.gov/21869457/

Dietary spermidine improves cognitive function https://pubmed.ncbi.nlm.nih.gov/33852843/

The positive effect of spermidine in older adults suffering from dementia : First results of a 3-month trial https://pubmed.ncbi.nlm.nih.gov/33211152/

The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/30388439/

Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline https://pubmed.ncbi.nlm.nih.gov/29315079/

A review of dietary polyamines: Formation, implications forgrowth and health and occurrence in foods https://www.sciencedirect.com/science/article/abs/pii/S0308814604002961

In vitro digestion of spermidine and amino acids in fresh and processed Agaricus bisporus mushroom https://pubmed.ncbi.nlm.nih.gov/33233206/

Decrease in polyamines with aging and their ingestion from food and drink https://pubmed.ncbi.nlm.nih.gov/16428322/

Fasting Drives The Geroprotective Effects Of A Calorie-Restricted Diet

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Paper referenced in the video:

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice https://www.nature.com/articles/s42255-021-00466-9

Attempting To Further Reduce Biological Age: hs-CRP

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Levine’s Biological age calculator is embedded as an Excel file in this link: https://michaellustgarten.wordpress.com/2019/09/09/quantifying-biological-age/

Papers referenced in the video:

The baseline levels and risk factors for high-sensitive C-reactive protein in Chinese healthy population https://immunityageing.biomedcentral.com/articles/10.1186/s12979-018-0126-7

Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies https://pubmed.ncbi.nlm.nih.gov/33152050/

65 – 100% Lifespan Extension In Drosophila: A Conversation With Dr. Michael Rose

Part II: Use Of Machine Learning In Longevity Science: A Conversation With Dr. Michael Rose

Part III: Which Diet Is Optimal For Health: The Evolutionary Perspective

Full, 80-minute, unedited video:

Papers referenced in the videos:

Can human aging be postponed? https://pubmed.ncbi.nlm.nih.gov/10614072/

Paper referenced in the video: Diet and Botanical Supplementation: Combination Therapy for Healthspan Improvement? https://pubmed.ncbi.nlm.nih.gov/32924860/

Dr. Rose’s website: https://55theses.org/

Insulin Sensitivity Is A Hallmark Of Longevity

HOMA calculator: https://www.omnicalculator.com/health…

Papers referenced in the video:

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice https://pubmed.ncbi.nlm.nih.gov/24175…

Glucose regulation and oxidative stress in healthy centenarians https://pubmed.ncbi.nlm.nih.gov/12543…

Distribution of blood glucose and prevalence of diabetes among centenarians and oldest-old in China: based on the China Hainan Centenarian Cohort Study and China Hainan Oldest-old Cohort Study https://pubmed.ncbi.nlm.nih.gov/32643…

Prevalence and Ethnic Pattern of Diabetes and Prediabetesin China in 2013 https://pubmed.ncbi.nlm.nih.gov/28655…

Families enriched for exceptional longevity also have increased health-span: findings from the long life family study https://pubmed.ncbi.nlm.nih.gov/24350…