Tag Archives: Muscle

A Higher Kynurenine/Tryptophan Ratio Is Associated With Lower Muscle Mass

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Papers referenced in the video:
Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging
https://pubmed.ncbi.nlm.nih.gov/34117761/

Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality The Hordaland Health Study https://pubmed.ncbi.nlm.nih.gov/26823439/

The mediating role of kynurenine pathway metabolites on the relationship
between inflammation and muscle mass in oldest-old men
https://pubmed.ncbi.nlm.nih.gov/38761087/

Metformin Impairs Exercise Training-Related Improvements In Older Adults

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Papers referenced in the video:

Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a https://pubmed.ncbi.nlm.nih.gov/34725961/

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double-blind, placebo-controlled, multicenter trial: The MASTERS trial https://pubmed.ncbi.nlm.nih.gov/31557380/

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults https://pubmed.ncbi.nlm.nih.gov/30548390/

New publications!

Paper #1: Here I propose that the poor muscle composition (muscle that has fat in it) found in older adults may be related to an increased systemic microbial burden:

exp ger.png

https://www.ncbi.nlm.nih.gov/pubmed/29030163

 

Paper #2: In this review, we discuss the emerging gut-muscle axis:

gg ml review.png

https://www.ncbi.nlm.nih.gov/pubmed/29058056

 

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