Here’s the first interview clip (of a series) with Modern Healthspan on YouTube where we discuss the role of the microbiome on health and longevity: Part II: Skin, Oral Microbiome & Immune System Part III: Optimal Health with Soluble Fiber Part IV – Microbial Burden & Hallmarks of Aging Part […]
Disease
LDL is arguably the most debated biomarker in terms of what’s optimal for health. In the video, I present data showing that 100 – 140, not 50 – 70 mg/dL may be optimal in terms of minimizing disease risk and maximizing longevity.
White blood cells (WBCs) comprise many different cell types, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. Neutrophils, lymphocytes, and monocytes account for ~99% of WBCs, and accordingly, in the video I propose optimal ranges for these cell types in terms of health and longevity.
Meta-analysis for the association between HDL with all-cause mortality risk has identified HDL levels 55 – 60 mg/dL range as optimal. However, that data includes subjects up to 85y-in the video, I present data for 85y – 115yr olds that additionally suggests HDL in the 55 – 60 mg/dL range […]
Animal products, including meat, cheese, and eggs contain carnitine and choline, metabolites that are converted by gut bacteria into TMA, which is then converted by the liver into TMAO. Plasma levels of TMAO are associated with an increased risk of disease and death, so should we limit intake of these […]
After going on Joe Rogan’s podcast, Paul Saladino, MD, posted his show notes, which included his blood test results. Based on that data, is his biological age optimal while on a carnivore diet?
Cooking foods at temperatures higher than boiling produces advanced glycation end (AGE) products, which induce insulin resistance and inflammation, and shorten lifespan in mice. Similar data exists in humans for the effect of dietary AGE products on insulin resistance and inflammation, and a higher dietary AGE product intake is associated […]
In order to slow aging, it’s important to know how circulating biomarkers change during aging, and how these biomarkers are associated with risk of death for all causes. In this video, I discuss blood test data for the oldest old, including centenarians (100 – 104y), semi-centenarians (105 – 109y), and […]
A meta-analysis of 10 studies, including 80,139 subjects was recently published that shows a significantly reduced risk of death for all causes in association with higher total dietary fiber intakes (35-39g/day), when compared with lower fiber (Reynolds et al. 2019): Should we supplement with fiber, or get it from […]
In an earlier post (https://michaellustgarten.com/2019/09/15/drink-green-tea-reduce-and-all-cause-mortality-risk/), I reported that green tea consumption is associated with reduced risk of death for all causes. Now, there’s more recent data! Drinking more than 1 cup of green tea per day is associated with reduced all-cause mortality risk in a pooled analysis of 8 studies […]
Having a faster rate of epigenetic aging, as measured by the epigenetic age metric, AgeAccelGrim, is associated with a significantly increased risk of death for all causes in a variety of cohorts, including the Framingham Heart Study (FHS), the Women’s Health Initiative (WHI) study, the InChianti study, the Jackson Heart […]
In an earlier post, based on data from the Baltimore Longitidunal Study on Aging (BLSA), I suggested that total white blood cell (WBCs) counts between 3500 to 6000 cells per microliter of blood may be optimal for reducing disease risk and for maximizing longevity (https://michaellustgarten.com/2015/08/13/blood-testing-whats-optimal-for-wbc-levels/). However, within WBCs, neutrophils increase, […]
Microbiome Webinar featuring me, and Drs. Amy Proal and Cosmo Mielke! For more info, https://www.amazon.com/dp/B01G48A88A
