Tag Archives: calorie restriction

RDW Is A Significant Predictor Of Biological Age: Which Factors May Optimize It?

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NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Telomere and Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv
Use Code: CONQUERAGING

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

At-Home Metabolomics: https://iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout

Oral Microbiome (Enter Code: ConquerAging): https://www.bristlehealth.com/?ref=michaellustgarten

At-Home Blood Testing: https://getquantify.io/mlustgarten

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

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Papers referenced in the video:
An epigenetic biomarker of aging for lifespan and healthspan
https://pubmed.ncbi.nlm.nih.gov/29676998/

Red blood cell distribution width and cardiovascular diseases https://pubmed.ncbi.nlm.nih.gov/26623117/

Omega-3 index is directly associated with a healthy red blood cell distribution width
https://pubmed.ncbi.nlm.nih.gov/34839221/

Red blood cell distribution width is significantly associated with aging and gender
https://pubmed.ncbi.nlm.nih.gov/24897405/

Red cell distribution width associations with clinical outcomes: A population-based cohort study https://pubmed.ncbi.nlm.nih.gov/30865651/

Epigenetic Age Test #6: My Youngest Data For Horvath, DunedinPACE

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Discount Links:
Telomere Length, Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv
Use Code: CONQUERAGING

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome (Enter Code: ConquerAging): https://www.bristlehealth.com/?ref=michaellustgarten

At-Home Blood Testing: https://getquantify.io/mlustgarten

Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

At-Home Metabolomics: https://iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout

If you’d like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca

Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/

——————————————————————————————————————————-Papers referenced in the video:

Underlying features of epigenetic aging clocks in vivo and in vitro
https://pubmed.ncbi.nlm.nih.gov/32930491/

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial
https://www.nature.com/articles/s43587-022-00357-y

Telomere Length Test #6: Correlations With Diet

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Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Discount Links:
Telomere Length, Epigenetic Testing: Trudiagnostic.pxf.io/R55XDv
Use Code: CONQUERAGING

NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Use Code: ConquerAging At Checkout

Green Tea: https://www.ochaandco.com/?ref=conqueraging

Oral Microbiome (Enter Code: ConquerAging): https://www.bristlehealth.com/?ref=michaellustgarten

At-Home Blood Testing: https://getquantify.io/mlustgarten

Diet Tracking: https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

At-Home Metabolomics: https://iollo.com?ref=michael-lustgarten Use Code: CONQUERAGING At Checkout

If you’d like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca

Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-spring.com/

——————————————————————————————————————————-Papers referenced in the video:

Telomeres and the natural lifespan limit in humans https://pubmed.ncbi.nlm.nih.gov/28394764/

Mid-life leukocyte telomere length and dementia risk: An observational and mendelian randomization study of 435,046 UK Biobank participants https://pubmed.ncbi.nlm.nih.gov/37254630/

Epigenetic Tests #1 and 2: Horvath, Hannum, DunedinPACE

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TruDiagnostic Discount Link (Epigenetic Testing)
CONQUERAGING!
https://bit.ly/3Rken0n

Bristle Discount Link (Oral microbiome quantification):
ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

Cronometer Discount Link (Daily diet tracking):
https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

Support the channel with Buy Me A Coffee!
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Papers referenced in the video:
Underlying features of epigenetic aging clocks in vivo and in vitro
https://pubmed.ncbi.nlm.nih.gov/32930491/

DNA methylation‐based measures of biological age: meta‐analysis predicting time to death
https://pubmed.ncbi.nlm.nih.gov/27690265/

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring
https://pubmed.ncbi.nlm.nih.gov/26678252/

DunedinPACE, a DNA methylation biomarker of the pace of aging
https://pubmed.ncbi.nlm.nih.gov/35029144/

Effect of Long-Term Caloric Restriction on DNA Methylation Measures of BiologicalAging in Healthy Adults: CALERIE™ Trial Analysis
https://www.medrxiv.org/content/10.1101/2021.09.21.21263912v1.full.pdf

Fasting Without Calorie Restriction Extends Lifespan

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Bristle Discount Link (Oral microbiome quantification):
ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

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https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

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Paper referenced in the video:
Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories
https://pubmed.ncbi.nlm.nih.gov/30197301/

Lifespan Extension With Calorie Restriction, Fasting, And Circadian Alignment

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Join us on Patreon!
https://www.patreon.com/MichaelLustgartenPhD

Bristle Discount Link (Oral microbiome quantification):
ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

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https://shareasale.com/r.cfm?b=1390137&u=3266601&m=61121&urllink=&afftrack=

You can support the channel by buying me a coffee!
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Papers referenced in the video:
Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice
https://www.nature.com/articles/s42255-021-00466-9

Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice
https://pubmed.ncbi.nlm.nih.gov/35511946/

Fasting Drives The Geroprotective Effects Of A Calorie-Restricted Diet

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Paper referenced in the video:

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice https://www.nature.com/articles/s42255-021-00466-9

Insulin Sensitivity Is A Hallmark Of Longevity

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HOMA calculator: https://www.omnicalculator.com/health…

Papers referenced in the video:

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice https://pubmed.ncbi.nlm.nih.gov/24175…

Glucose regulation and oxidative stress in healthy centenarians https://pubmed.ncbi.nlm.nih.gov/12543…

Distribution of blood glucose and prevalence of diabetes among centenarians and oldest-old in China: based on the China Hainan Centenarian Cohort Study and China Hainan Oldest-old Cohort Study https://pubmed.ncbi.nlm.nih.gov/32643…

Prevalence and Ethnic Pattern of Diabetes and Prediabetesin China in 2013 https://pubmed.ncbi.nlm.nih.gov/28655…

Families enriched for exceptional longevity also have increased health-span: findings from the long life family study https://pubmed.ncbi.nlm.nih.gov/24350…

SIRT6 Positively Affects The Hallmarks Of Aging And Extends Lifespan

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Papers referenced in the video:

Sirtuins, Healthspan, and Longevity in Mammals https://www.sciencedirect.com/science…

Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH https://pubmed.ncbi.nlm.nih.gov/24011…

Resveratrol improves health and survival of mice on a high-calorie diet https://pubmed.ncbi.nlm.nih.gov/17086…

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice https://pubmed.ncbi.nlm.nih.gov/20974…

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer https://www.nature.com/articles/ncomm…

Restoration of energy homeostasis by SIRT6 extends healthy lifespan https://pubmed.ncbi.nlm.nih.gov/34050…

The sirtuin SIRT6 regulates lifespan in male mice https://pubmed.ncbi.nlm.nih.gov/22367…

SIRT6 in Senescence and Aging-Related Cardiovascular Diseases https://pubmed.ncbi.nlm.nih.gov/33855…

Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling https://pubmed.ncbi.nlm.nih.gov/26940…

Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6 https://pubmed.ncbi.nlm.nih.gov/27101…

A Comprehensive Analysis into the Therapeutic Application of Natural Products as SIRT6 Modulators in Alzheimer’s Disease, Aging, Cancer, Inflammation, and Diabetes https://pubmed.ncbi.nlm.nih.gov/33920…

Acute Exercise Leads to Regulation of Telomere Associated Genes and MicroR A Expression in Immune Cells https://pubmed.ncbi.nlm.nih.gov/24752…

The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men https://pubmed.ncbi.nlm.nih.gov/32919…

High FGF21, Low Insulin And Glucose: A Pro-Longevity Strategy?

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Papers referenced in the video:

FGF21 and Chronic Kidney Disease: https://www.sciencedirect.com/science…

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice: https://www.ncbi.nlm.nih.gov/pmc/arti…

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21: https://pubmed.ncbi.nlm.nih.gov/18585…

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: https://pubmed.ncbi.nlm.nih.gov/32877…

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression: https://pubmed.ncbi.nlm.nih.gov/31773…

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice: https://www.ncbi.nlm.nih.gov/pmc/arti…

Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses: https://pubmed.ncbi.nlm.nih.gov/28552…

Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer’s disease in comparison with healthy aging: https://pubmed.ncbi.nlm.nih.gov/33131…

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue: https://pubmed.ncbi.nlm.nih.gov/30043…

Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals: https://pubmed.ncbi.nlm.nih.gov/26042…

Lower All-Cause, Cardiovascular, and Cancer Mortality in Centenarians’ Offspring: https://pubmed.ncbi.nlm.nih.gov/15571…

Favorable Glucose Tolerance and Lower Prevalence of Metabolic Syndrome in Offspring without Diabetes Mellitus of Nonagenarian Siblings: The Leiden Longevity Study: https://pubmed.ncbi.nlm.nih.gov/20398…