Tag Archives: Quantified Self

Aspartate Aminotransferase: What’s Optimal, And Can It Be Improved?

Papers referenced in the video:

Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase: Finding Aspartate Aminotransferase a Better Mortality Predictor for All-Cause and Liver-Related than Alanine Aminotransferase https://pubmed.ncbi.nlm.nih.gov/31425…

Implication of liver enzymes on incident cardiovascular diseases and mortality: A nationwide population-based cohort study https://pubmed.ncbi.nlm.nih.gov/29491…

Selenium: How Much Is Optimal For Health?

For those who track their diet, eating only the RDA for many nutrients may not optimize health. For example, the RDA for selenium is 55 micrograms per day, but is that amount optimal for reducing risk of death for all causes?

VLDL Increases During Aging, And Is Associated With Adverse Cardiovascular Outcomes

Papers referenced in the video:

Remnant Cholesterol and Atherosclerotic Cardiovascular Disease Risk: https://www.jacc.org/doi/10.1016/j.ja…

The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling: https://www.sciencedirect.com/science…

Joint distribution of lipoprotein cholesterol classes. The Framingham study: https://pubmed.ncbi.nlm.nih.gov/6573877/

Long-term coronary heart disease risk associated with very-low-density lipoprotein cholesterol in Chinese: the results of a 15-Year Chinese Multi-Provincial Cohort Study (CMCS): https://pubmed.ncbi.nlm.nih.gov/20223…

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease: https://pubmed.ncbi.nlm.nih.gov/33272…

Remnant cholesterol and coronary atherosclerotic plaque burden assessed by computed tomography coronary angiography: https://pubmed.ncbi.nlm.nih.gov/30870…

Premature myocardial infarction is strongly associated with increased levels of remnant cholesterol: https://pubmed.ncbi.nlm.nih.gov/26687…

Homocysteine Increases During Aging, But Can Be Reduced With Diet And Targeted Supplementation

Papers referenced in the video:

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi.nlm.nih.gov/32130…

Comparison of the effects of nicotinic acid and nicotinamide degradation on plasma betaine and choline levels: https://pubmed.ncbi.nlm.nih.gov/27567…

Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study: https://pubmed.ncbi.nlm.nih.gov/7474221/

Total plasma homocysteine values among elderly subjects: findings from the Maracaibo Aging Study: https://pubmed.ncbi.nlm.nih.gov/16959…

Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies: https://www.ncbi.nlm.nih.gov/pmc/arti…

Hyperhomocysteinemia and risk of incident cognitive outcomes: An updated dose-response meta-analysis of prospective cohort studies: https://pubmed.ncbi.nlm.nih.gov/30826…

Association between Homocysteine Levels and All-cause Mortality: A Dose-Response Meta-Analysis of Prospective Studies: https://www.nature.com/articles/s4159…

Quantifying Biological Age: Blood Test #2 in 2021

Paper references for Levine’s Phenotypic Age calculator and aging.ai:

An epigenetic biomarker of aging for lifespan and healthspan: https://pubmed.ncbi.nlm.nih.gov/29676…

Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations:

https://pubmed.ncbi.nlm.nih.gov/29340…

HDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range

In November 2020, I made a HDL video based on a meta-analysis in ~3.4 million subjects that was published in July 2020. In Dec 2020, a larger study (n=15.8 million subjects) was published-those data are presented in the video, and compared against the meta-analysis.

In addition, I’ve tested my HDL 2 more times since November 2020, so how’s my progress for getting it into the optimal range? Also, I attempt to derive clinical significance by identifying correlations for higher HDL with lower Lp(a) and hs-CRP.

Video link: https://www.youtube.com/watch?v=MUuKlpyvZaU

Quantifying Biological Age: Blood Test #1 in 2021

Results for my first blood test in 2021 are in-what’s my biological age, and how am I optimizing it?

If you’re interested in calculating your biological age, the spreadsheet is included as an Excel file in this link: