Author Archives: Michael Lustgarten

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About Michael Lustgarten

Ph.D, Physiology, University of Texas Health Science Center at San Antonio, 2009 B.S., Biochemistry, Queens College, 2003 B.A, English Textual Studies, 1994, Syracuse University

Metformin Impairs Exercise Training-Related Improvements In Older Adults

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Papers referenced in the video:

Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a https://pubmed.ncbi.nlm.nih.gov/34725961/

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double-blind, placebo-controlled, multicenter trial: The MASTERS trial https://pubmed.ncbi.nlm.nih.gov/31557380/

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults https://pubmed.ncbi.nlm.nih.gov/30548390/

Quantifying Biological Age: Blood Test #5 in 2021

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Links to biological age calculators:

Levine’s PhenoAge calculator is embedded as an Excel file: https://michaellustgarten.com/2019/09/09/quantifying-biological-age/

aging.ai

Papes referenced in the video:

Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies https://www.bmj.com/content/348/bmj.g1903

Fisetin is a senotherapeutic that extends health and lifespan https://pubmed.ncbi.nlm.nih.gov/30279143/

Fruit And Vegetable Intake: How Many Servings/Day Is Optimal?

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Paper referenced in the video:

Fruit and Vegetable Intake and Mortality Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies

https://pubmed.ncbi.nlm.nih.gov/33641343/

Fasting Drives The Geroprotective Effects Of A Calorie-Restricted Diet

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Paper referenced in the video:

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice https://www.nature.com/articles/s42255-021-00466-9

Chocolate Intake Is Associated With Reduced All-Cause And Cause-Specific Mortality Risk

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Papers referenced in the video: Chocolate consumption and all-cause and cause-specific mortality in a US population: a post hoc analysis of the PLCO cancer screening trial https://pubmed.ncbi.nlm.nih.gov/34329196/

Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons https://pubmed.ncbi.nlm.nih.gov/15755830/

Other RCTs for the effect of chocolate on health: Sub-Chronic Consumption of Dark Chocolate Enhances Cognitive Function and Releases Nerve Growth Factors: A Parallel-Group Randomized Trial https://pubmed.ncbi.nlm.nih.gov/31744119/

Habitual cocoa intake reduces arterial stiffness in postmenopausal women regardless of intake frequency: a randomized parallel-group study https://pubmed.ncbi.nlm.nih.gov/27881914/

High Flavonoid Cocoa Supplement Ameliorates Plasma Oxidative Stress and Inflammation Levels While Improving Mobility and Quality of Life in Older Subjects: A DoubleBlind Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/31056655/

Dietary epicatechin improves survival and delays skeletal muscle degeneration in aged mice https://pubmed.ncbi.nlm.nih.gov/30096038/

USDA flavonoid database https://www.ars.usda.gov/arsuserfiles/80400525/data/flav/flav_r03-1.pdf

Epidemiological Studies vs n=1: What’s Optimal For Dietary Cholesterol?

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Papers referenced in the video:

Dietary Intakes of Eggs and Cholesterol in Relation to All-Cause and Heart Disease Mortality: A Prospective Cohort Study https://pubmed.ncbi.nlm.nih.gov/32400247/

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality https://pubmed.ncbi.nlm.nih.gov/30874756/

Dietary fibre intake is associated with increased skeletal muscle mass and strength (Paper Review)

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Papers referenced in the video:

Higher dietary fibre intake is associated with increased skeletal muscle mass and strength in adults aged 40 years and older https://pubmed.ncbi.nlm.nih.gov/34585…

A defined, plant-based diet utilized in an outpatient cardiovascular clinic effectively treats hypercholesterolemia and hypertension and reduces medications https://pubmed.ncbi.nlm.nih.gov/29575…

Attempting To Further Reduce Biological Age: hs-CRP

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Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD

Levine’s Biological age calculator is embedded as an Excel file in this link: https://michaellustgarten.wordpress.com/2019/09/09/quantifying-biological-age/

Papers referenced in the video:

The baseline levels and risk factors for high-sensitive C-reactive protein in Chinese healthy population https://immunityageing.biomedcentral.com/articles/10.1186/s12979-018-0126-7

Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies https://pubmed.ncbi.nlm.nih.gov/33152050/

Attempting To Further Reduce Biological Age: Reducing Glucose (Without Messing Up Other Biomarkers)

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Join us on Patreon! https://www.patreon.com/MichaelLustga…

Levine’s Biological age calculator is embedded as an Excel file in this link: https://atomic-temporary-71218033.wpcomstaging.com/2019/09…