In the video below, Steve Hill from Lifespan.io and I talk about findings from a recent paper (https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200306) that supports a role for the gut microbiome on Alxheimer’s disease. Check it out!
Germ-free mice (animals don’t have a microbiome) live longer than microbiome-containing mice, but it’s impractical for people to live in a bubble for their entire lifespan. As a more practical approach, which microbiome-derived factors impact lifespan, and can they be modified?
Dietary supplementation with acarbose increases lifespan, and one reason for that may involve reduced circulating levels of glucose, but the other side of that story involves increased gut bacterial production of short chain fatty acids (SCFAs). Whether acarbose will increase lifespan in people is unknown, and with the goal of increasing lifespan, are there other ways to increase SCFAs?
How does the gut microbiome and its metabolic products affect muscle mass, muscle composition, and physical function? In this presentation, I review the evidence, then I present recent data from our group.
Here’s a link to a recent interview,
Including:
And much more!
Here’s my latest academic paper!
Have a listen, I was on Generation Bold Radio yesterday, 9.14.2019!
https://www.generationboldradio.us/
Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults
https://www.sciencedirect.com/science/article/pii/S0531556519304772
Microbiome Webinar featuring me, and Drs. Amy Proal and Cosmo Mielke!
For more info,
https://www.amazon.com/dp/B01G48A88A
Michael Lustgarten 